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Germ cell development is a step-wise process that ensures the progression of the life cycle due to their unique ability to transmit their genome from one generation to the next. In the mouse, the precursors of germ cells, the Primordial Germ Cells (PGCs), arise at the onset of gastrulation. Here we discuss how PGCs acquire their fate in the epiblast and outline their development until their arr...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2006
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb0206-112